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Aloe Vera (Ghrita Kumari): 9 Benefits And 6 Side Effects

Aloe Vera Juice Benefits And Side Effects

Aloe Vera Juice Benefits And Side Effects

Benefits Of Aloe Vera

Aloe vera has been used since time immemorial to treat skin infections and boost immunity. It is also known to lower cholesterol, speed up the healing process of wounds, and reduce stress. It might even boost memory, treat neurodegenerative disorders, and lower blood sugar levels. However, studies have found that prolonged use could lead to diarrhea, dehydration, kidney diseases, or liver failure.

Aloe vera, kumari, or ghrita kumari, has multiple uses in ayurveda and is known to balance all three doshas. It is especially effective in treating diseases originating from vata imbalance.

The Egyptians called aloe vera “the plant of immortality,” the Native Americans called it “the wand of heaven,” and Indians called it “kumari,” in reference to the youthful beauty of a young girl. It’s no wonder then that most of us equate this succulent plant to beauty and good health. True to this, aloe vera is favored by both skin care professionals and doctors alike. Aloe vera juice too is catching on in popularity. It is a storehouse of vitamins like A, C, E, B1, B2, B3 (niacin), B6, choline, and folate – however, contrary to popular belief, aloe vera itself does not contain vitamin B12; it enhances the absorption of B12 supplements. It also contains minerals like calcium, magnesium, zinc, chromium, selenium, sodium, iron, potassium, copper, and manganese. Not just that, aloe vera contains 20 of the 22 required amino acids and 7 of the 8 essential ones. Here’s a ready reckoner of health benefits of aloe vera.

1. Relieves Constipation

When you cut an aloe leaf and keep it upright, you may notice a yellow latex draining out. This contains a chemical called aloin, a type of anthraquinone which gives aloe its laxative properties. However, it can cause severe diarrhea in some people.

The most commonly noted health benefit of aloe vera is in relieving constipation. Usually the yellow latex from the leaf is had to tackle constipation. It contains an organic compound called anthraquinone, which has potent laxative properties and can stimulate bowel movements to tackle constipation. In ayurveda, kumarisaar, a formulation using the dried yellow latex, is used to treat constipation and other digestive disorders.

2. May Treat Gastrointestinal Disorders

Ayurvedic texts refer to aloe vera as “pleehahara” and “yakrut vruddhihara,” referring to its benefit in treating spleen (pleeha) and liver (yakrut) enlargements and even hepatitis. Kumaryasava, an ayurvedic formulation using fermented aloe vera juice, is used to treat these conditions.

While research on these areas is lacking, aloe vera does seem to have other digestive benefits. It might reduce bloating and heartburn and aid digestion by increasing the number of healthy bacteria in the gut.1 2 There’s also some evidence that aloe vera might help with ulcerative colitis. One small clinical study looked into the effects of 100 ml of aloe vera gel on 44 people with ulcerative colitis when taken orally. After 4 weeks, it was found that there was a moderate benefit on the symptoms of the condition such as bloating and inability to empty bowels. That said, while aloe vera might help in the initial stages of ulcerative colitis when constipation is the dominant symptom, it might have an adverse effect in the later stages when diarrhea becomes dominant.3 So it is imperative that you first consult a professional and stick to the recommended dosage.

3. Lowers Cholesterol Levels

Blend some aloe gel with a citrus fruit juice or even a smoothie with green leafs. All of these are known to balance the cholesterol levels.

If your cholesterol levels are high, you may incorporate aloe vera juice into your diet. Studies have shown that a compound called beta-sitosterol present in aloe vera can increase the HDL “good” cholesterol levels in your body which, in turn, lowers the LDL “bad” cholesterol. By bringing your cholesterol levels under control, aloe vera can also reduce your risk of related conditions like heart disease, stroke, diabetes, and high blood pressure.4 5

4. Boosts Immunity

If you have a weak immunitys, it might do you good to include aloe vera in your diet. Studies have found that it could enhance white blood cell activity and promote the production of certain proteins that help fight viral infection.6 7 Aloe vera also contains complex carbohydrates, which have shown an immunomodulatory effect.8 Aloe vera also has antibacterial, antifungal, and antiviral properties, which makes it effective in preventing infections.

5. May Manage Type 2 Diabetes

Before taking aloe vera, consult a professional if you take medications to reduce blood glucose. Also stop taking aloe vera 2 weeks before a surgery.

When it comes to managing high blood glucose levels, aloe vera might come in handy. But the evidence on its direct effect on blood glucose levels seems to be mixed. Certain studies have noted a blood glucose reduction in women with type 2 diabetes who consumed aloe vera pulp, while other studies did not. The exact mechanism isn’t clear either. One line of reasoning is that aloe vera lowers cortisol levels in the blood and improves glucose metabolism. Besides, it also lowers the levels of bad cholesterol, a comorbid factor in diabetes.9 10

6. Reduces Stress

If you’ve been feeling stressed of late, consider using aloe vera. Studies have found that beta-glucan (sugars that are found in the cell walls of bacteria, fungi, yeasts, algae, lichens, and plants) in aloe vera lowers levels of cortisol, the stress hormone, in your body.11 Besides this, ayurveda considers aloe vera to be a rasayana or an adaptogen, a substance that supports the body’s ability to deal with stress, whether that stress is from anxiety, fatigue, trauma, or even infection.

7. May Improve Memory And Fight Neurodegenerative Diseases

Apart from relieving stress, certain studies have hinted at the possibility of aloe vera improving brain function. In one such study, it was observed that aloe vera extract slightly altered the function of neurotransmitters. This, in turn, was found to improve memory and reduce depression.12 13 Another study found that supplementation with a supplement containing aloe vera significantly improved the symptoms of Alzheimer’s in both men and women.14

8. Makes The Skin Healthy And Youthful

When you scoop out aloe gel, scoop it from the middle of the leaf, taking care to not scrape the green part too closely.

Of all the uses of aloe vera, skin care tops the list. Aloe vera has anti-inflammatory, anti-bacterial, and anti-fungal properties, which make it effective against acne and skin infections like eczema and psoriasis. Besides this, it improves skin elasticity, promotes skin cell regeneration by boosting collagen production, and protects the skin from harmful UV rays, in turn preventing wrinkles and dark spots. Aloe vera also moisturizes the skin and is loaded with skin-friendly vitamin C, keeping it healthy and supple.15 16

9. Treats Wounds

When you apply aloe vera gel to a wound, don’t cover it with a bandage. To facilitate healing, aloe vera requires open air. However, avoid using aloe vera to treat deep wounds.

By increasing the collagen production and stimulating cell regeneration, aloe vera can help treat wounds and cuts. It seals off wounds by binding the skin tissues and works as an astringent. In addition to this, aloe vera gel can be used to treat burns, insect bites, stings, and even sunburns.17

However, the University of Maryland recommends that you try out other gentler herbs like senna or cascara before aloe vera, as the latter could cause intense cramping and dehydration in some cases.18

Side Effects Of Aloe Vera

Aloe vera is helpful but in moderation. Much of its side effects come from a class of organic compounds called anthraquinones, most concentrated near the green part of the leaf and in the yellow latex beneath the leaf. Aloe latex contains aloin, a form of anthraquinone, that is known for its potent laxative effects. And while it helps ease constipation, aloin can cause severe diarrhea as well as trigger allergic reactions. Here’s a look at the side effects of aloe vera:

1. Diarrhea

Even when it’s taken at low doses, aloe vera might prove to be harmful if you’ve got a sensitive stomach. It can cause nausea, vomiting, and diarrhea. In addition to this, it might trigger abdominal cramps and worsen the symptoms of hemorrhoids. This is especially true with prolonged use of aloe latex or supplements that contain it. Children under the age of 12 may especially experience gastrointestinal upset if aloe is ingested orally.19 This is why, in 2002, the USFDA ruled that all over-the-counter aloe latex be removed from the market or at least reformulated without aloe latex. Today, the aloe products available in the US are not regulated by the FDA, and whether they contain the gel or the latex cannot be determined by a lay user because these products do not contain information about the aloin content.20 21

2. Dehydration

As the laxative properties of aloe vera can lead to severe diarrhea, you may develop severe dehydration as a side effect and develop an electrolyte imbalance.22 Keeping this in mind, aloe vera should be used cautiously in people who already are on diuretics (which increase the excretion of potassium from the body).23 24

4. Allergic Reactions

As with most herbal remedies, it’s important to check for any allergies before using aloe vera gel. The green outer layer of the leaf as well as the yellow latex are not good for the skin. So if the gel has been scooped out from near the green layer, there are chances of skin irritation. You might even be allergic to aloe itself. Do a patch test, and if your skin doesn’t tolerate aloe well, skip drinking the juice too.25

5. Muscle Weakness

Supplementation with aloe vera has been shown to weaken muscles, especially in diabetics. Although the exact mechanism behind this is uncertain, it is generally accompanied by abdominal cramps. In addition to this, the studies that looked into this side effect only noted the effects of short-term (6–12 weeks) supplementation. Further studies are required to fully understand the long-term benefits and side effects.26

6. Risk Of Cancer

One study conducted on rats found that when non-decolorized whole-leaf extracts of aloe vera were added to water, they caused cancer in female rats. However, decolorized aloe extract did not. Decolorizing refers to the process of removing the anthraquinones from aloe vera.27 28 This points to the fact that aloin and other anthraquinones are the main carcinogenic compounds in aloe vera.

Besides this, most popular brands of aloe vera juice contain sodium benzoate as a preservative, which is added to inhibit microbial growth. However, when combined with citric acid (ascorbic acid), sodium benzoate forms benzene, a known carcinogen. At the moment, there is an ongoing debate about the effect of benzene in humans. That said, it is worth keeping in mind before consuming aloe vera juice.29

How To Use Aloe Vera

Aloe vera has been used traditionally to treat amenorrhea, or the absence of period, and pregnant and breastfeeding women are advised to avoid consuming aloe vera in both gel or latex form. Research has linked them to possible development risks to the fetus.30

Although aloe vera has been used traditionally to treat various diseases, it’s best to consult a healthcare professional before using it. This is especially true if you’re planning on consuming aloe juice or supplements.

Commercial aloe vera juice is made from the whole leaf and not just the gel and hence has a risk of a high aloin content. A decolorizing procedure is usually followed where the anthraquinones are removed so that the aloin content falls below 10 ppm. But right now, there’s no rule for manufacturers to label the aloin content. So you may not even know how much you are consuming.

Aloin may be present in cosmetic products as well and may irritate your skin if it’s present in large amounts. The FDA rules that for cosmetic purposes, an aloin content up to 50 ppm is safe.31

Rather than relying on an OTC aloe product to ease your constipation or an aloe juice for other health benefits, make your aloe juice at home. However, exercise extreme caution in isolating the gel from the latex, and always consult your doctor first.

  • Cut out an aloe leaf from the plant and set it upright in a bowl to let the toxic aloe latex (an yellow-colored chemical called aloin) drain out completely.
  • Scoop out the gel from the middle of the leaf, taking care not to scrape too close to the green outer layer. This can be used both topically and orally.

Aloe Vera Juice: Blend the gel and mix it with water or another fruit juice. Aloe juice is bitter, so you may not like having the concentrated juice. The standard ayurvedic dosage of the juice is 10–20 ml a day.32

Ayurvedic Formula For Constipation: Blend 10 g of the gel with 2 g rock salt, and then boil it to evaporate the water. Have this in a dose of 3–6 g once a day.33

References   [ + ]

1, 7. Qadir, M. Imran. “Medicinal and cosmetological importance of Aloe vera.” Int J Nat Ther 2 (2009): 21-26.
2. Foster, Meika, Duncan Hunter, and Samir Samman. Evaluation of the nutritional and metabolic effects of Aloe vera. Vol. 3. chapter, 2011.
3. Crohn’s & Colitis Program, Patient Information Guide. The University Of Michigan.
4. Chandrakar, Mamata, Sachin Palekar, Sudhir Chirade, and S. Hafiz. “Hypocholesterolemic effect of Aloe vera (L.) extract on high cholesterol fed calotes versicolor daudin.” Asian J Exp Sci 22, no. 3 (2008): 295-298.
5. Palermo, Francesco A., Paolo Cocci, Mauro Angeletti, Alberto Felici, Alberta Maria Polzonetti-Magni, and Gilberto Mosconi. “Dietary Aloe vera components’ effects on cholesterol lowering and estrogenic responses in juvenile goldfish, Carassius auratus.” Fish physiology and biochemistry 39, no. 4 (2013): 851-861.
6. Vahedi, Ghasem, Mehdi Taghavi, Amin Kheirollahzade Maleki, and Reza Habibian. “The effect of Aloe vera extract on humoral and cellular immune response in rabbit.” African Journal of Biotechnology 10, no. 26 (2011): 5225-5228.
8. Hamman, Josias H. “Composition and applications of Aloe vera leaf gel.” Molecules 13, no. 8 (2008): 1599-1616.
9. Okyar, Alper, Ayşe Can, Nuriye Akev, Gül Baktir, and Nurhayat Sütlüpinar. “Effect of Aloe vera leaves on blood glucose level in type I and type II diabetic rat models.” Phytotherapy Research 15, no. 2 (2001): 157-161.
10. Aloe Vera and Diabetes. Diabetes, UK.
11. Montoya, Luz N. Franco, Talísia P. Martins, Rodrigo Y. Gimbo, Fábio S. Zanuzzo, and Elisabeth C. Urbinati. “β-Glucan-induced cortisol levels improve the early immune response in matrinxã (Brycon amazonicus).” Fish & shellfish immunology 60 (2017): 197-204.
12. Halder, Sumita, Ashish K. Mehta, and Pramod K. Mediratta. “Aloe vera improves memory and reduces depression in mice.” Nutritional Neuroscience 16, no. 6 (2013): 250-254.
13. Salehi, Bahareh, Esmaeil Biazar, Mahsa Hadipour Jahromi, and Hanie Akbari Romani. “Antidepressant effects of Aloe vera hydroalcoholic extract.” Journal of Paramedical Sciences 2, no. 3 (2011).
14. Lewis, John E., H. Reginald McDaniel, Marc E. Agronin, David A. Loewenstein, Jorge Riveros, Rafael Mestre, Mairelys Martinez et al. “The effect of an aloe polymannose multinutrient complex on cognitive and immune functioning in Alzheimer’s disease.” Journal of Alzheimer’s Disease 33, no. 2 (2013): 393-406.
15. Cho, Soyun, Serah Lee, Min-Jung Lee, Dong Hun Lee, Chong-Hyun Won, Sang Min Kim, and Jin Ho Chung. “Dietary Aloe vera supplementation improves facial wrinkles and elasticity and it increases the type I procollagen gene expression in human skin in vivo.” Annals of Dermatology 21, no. 1 (2009): 6-11.
16. Why is Aloe Vera so Good for Skin Care? Evergreen Beauty College.
17. Aloe. University of Rochester Medical Center.
18. Constipation. University of Maryland Medical Center.
19, 30. Aloe vera — What is it good for? Columbia University.
20. Aloe Vera. National Institutes of Health.
21. Crohn’s & Colitis Program Patient Information Guide. University of Michigan.
22. Name of Herb: Aloe. The University Of California, Denver.
23.

3. Liver Or Kidney Disorders

Research indicates that ingesting aloe vera could lead to liver or kidney injury and inflammation. It was also found to worsen paracetamol-induced liver injury in rats. Thankfully, the condition is reversed once aloe vera is discontinued. While there are fewer studies that look into kidney failure in association with aloe vera gel, there is enough research to state that aloe latex consumption can cause renal failure.[ref]Parlati, Lucia, Cosmin Sebastian Voican, Katy Perlemuter, and Gabriel Perlemuter. “Aloe vera-induced acute liver injury: A case report and literature review.” Clinics and research in hepatology and gastroenterology 41, no. 4 (2017): e39-e42.

24. Samuhasaneetoa, Suchittra, and Sorrayut Kajornvuthidejb. “Negative effects of Aloe vera gel on paracetamol-induced liver injury in rats.” Science Asia 40 (2014): 42.
25. Aloe. University Of Rochester Medical Center.
26. Zhang, Yiyi, Wen Liu, Dan Liu, Tieyun Zhao, and Haoming Tian. “Efficacy of Aloe vera supplementation on prediabetes and early non-treated diabetic patients: a systematic review and meta-analysis of randomized controlled trials.” Nutrients 8, no. 7 (2016): 388.
27. Aloe Vera. National Toxicology Program.
28. Shao, A., A. Broadmeadow, G. Goddard, E. Bejar, and V. Frankos. “Safety of purified decolorized (low anthraquinone) whole leaf Aloe vera (L) Burm. f. juice in a 3-month drinking water toxicity study in F344 rats.” Food and chemical toxicology 57 (2013): 21-31.
29. Campbell, Ian Gavin A. “An overview of emerging trends in pathogen reduction in the processing of fruit juices.” (2014).
31. Cosmetic Ingredient Review Expert Panel. “Final report on the safety assessment of AloeAndongensis Extract, Aloe Andongensis Leaf Juice, aloe Arborescens Leaf Extract, Aloe Arborescens Leaf Juice, Aloe Arborescens Leaf Protoplasts, Aloe Barbadensis Flower Extract, Aloe Barbadensis Leaf, Aloe Barbadensis Leaf Extract, Aloe Barbadensis Leaf Juice, aloe Barbadensis Leaf Polysaccharides, Aloe Barbadensis Leaf Water, Aloe Ferox Leaf Extract, Aloe Ferox Leaf Juice, and Aloe Ferox Leaf Juice Extract.” International journal of toxicology 26 (2007): 1.
32, 33. Aloe Vera Benefits, Research, Home Remedies, Side Effects. Easyayurveda.

Disclaimer: The content is purely informative and educational in nature and should not be construed as medical advice. Please use the content only in consultation with an appropriate certified medical or healthcare professional.