How Often Should You Do An Estrogen Detox?

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An estrogen detox can be performed once a year and is encouraged even for men, as it can reduce the risk of prostate cancer. The typical benefits of enhancing estrogen metabolism are a reduced risk of hormone-related cancers, lighter periods, reductions in fibroids, improved fertility, and clearer skin. Read to know how to carry out an estrogen detox.

Sex hormones are produced in the body via the following assembly line:

  • Cholesterol
  • Pregnenolone
  • Progesterone
  • Androstenedione
  • Testosterone
  • Estradiol (one form of estrogen)

Estradiol is our end product, and when there is the right amount of our end product, it’s the liver’s job to take any extra and break it down through a series of steps known as Phase I and Phase II liver detoxification.

It is important to remove any excess estrogen so that these waste products don’t accumulate and do harm, such as promoting reproductive cancers. There are several ingredients required for the successful breakdown and clearance of estrogen and of chemicals, pollution, pesticides, etc. that can act like estrogen.

How Does Estrogen Breakdown Work?

Intake of cruciferous vegetables, flaxseeds, soy, and rosemary supply substances like indole-3-carbinol can help in this step.

The first step in estrogen breakdown is the conversion of estradiol to estrone. Estrone is then metabolised through Phase I liver detoxification (hydroxylation) into 2-hydroxyestrone.

This step requires vitamin B6, B12, and active folic acid (5MTHF).

The next step in estrogen breakdown is Phase II detoxification (methylation), which converts 2-hydroxyestrone to 2-methoxyestrone. The active folic acid is important as most of the folic acid from supplements is inactive.

Some people have a defective gene that doesn’t allow them to process folic acid properly. As a result, they cannot produce 5MTHF. This leads to sluggish liver detoxification.

Important Ingredients Required For The Breakdown

There are 3 final procedures the liver can do to 2-methoxyestrone to ready it for elimination. And certain ingredients are required for these procedures:

  • Glucuronidation requires glucaric acid
  • Methlyation requires active folic acid (5MTHF)
  • Sulfation requires sulfur

What Are The Possible Health Issues?

Absence of any of these ingredients results in an incomplete estrogen breakdown. This results in a build-up of estrogen, estrogen breakdown products, and other similar wastes in your system, resulting in multiple health problems:

  • Endometriosis1
  • Acne
  • Fibroids
  • Painful and heavy periods
  • Hormone-related cancers
  • Infertility and other hormone imbalance conditions

To treat these conditions, it is of utmost importance to supply the necessary components (in the form of supplements) for the successful completion of phase I, phase II, and the final packaging steps.2

What Are The Benefits Of Enhancing Estrogen Metabolism?

  • Reduced risk of hormone-related cancers
  • Lighter periods
  • Less cramping
  • Less breast tenderness
  • Reduced fibroids
  • Improved fertility
  • Clearer skin

When Should You Do An Estrogen Detox?

The timing depends on each individual and his or her particular symptoms. However, in general, I’d suggest such a detox for the average person once per year.

Should Men Do This Too?

Yes! Men produce estrogen as well! Excess estrogen and accumulation of estrogen-like chemicals such as bisphenol A can bind to estrogen receptors in men and promote diseases such as prostate cancer.3

References   [ + ]

1.Kitawaki, J., N. Kado, H. Ishihara, H. Koshiba, Y. Kitaoka, and H. Honjo. “Endometriosis: the pathophysiology as an estrogen-dependent disease.” The Journal of steroid biochemistry and molecular biology 83, no. 1 (2002): 149-155.
2.Hall, D. “Nutritional influences on estrogen metabolism.” Applied nutritional science reports 1 (2001): 1-8.
3.Nock, Nora L., Mine S. Cicek, Li Li, Xin Liu, Benjamin A. Rybicki, Andrea Moreira, Sarah J. Plummer, Graham Casey, and John S. Witte. “Polymorphisms in estrogen bioactivation, detoxification and oxidative DNA base excision repair genes and prostate cancer risk.” Carcinogenesis 27, no. 9 (2006): 1842-1848.
Pamela Frank
Star Expert

I believe in addressing the root of any health problem through diet, stress reduction, exercise and specific vitamins. minerals, amino acids, herbs and other natural supplements to provide lasting health improvement to my patients.

Pamela Frank
Star Expert

I believe in addressing the root of any health problem through diet, stress reduction, exercise and specific vitamins. minerals, amino acids, herbs and other natural supplements to provide lasting health improvement to my patients.

Post a Comment
Tracy Neely
Tracy Neely 5pts

Must of you article are so indirect just get to the information I don't want to look for it unfollow today.

Sonia Benson
Sonia Benson 5pts

This is one post of yours I don't get, u guys are great with useful info but this? I don't get . u guys didn't mention on how how do we know what to do?

Jena Gribble
Jena Gribble 5pts

Most of your articles are misleading. Unfollowing.

Annette Lombe
Annette Lombe 5pts

Time for one Rita Whodathexenbabe Lombe hey?!

Adrean Wynn
Adrean Wynn 5pts

there is no recipe for this i looked, the turds, got me, and they also mentioned soy, gross, soy is bad,

Patricia J. Paronett
Patricia J. Paronett 5pts

I'm sorry, people are not interested in piecing together information. When you put a tagine out there, please put the actual recipe for the actual cleanse you want people to know about...what's the formula for specifically an estrogen detox...not the website to a bunch of liver detox items that we have to read through and figure out. We read these articles because we don't have time to piece them together. We thank you for providing information but I think for me personally, It has to be practical and useful

Susan Day
Susan Day 5pts

I need all the oestrogen I can get.

Meaghen Slade
Meaghen Slade 5pts

Me either. . I don't see it on the page at all

RichardKing2 5pts

How long do you have ingest these supplements before moving on to the next phase? Anybody knows?

BiBi C. Bbc
BiBi C. Bbc 5pts

I can't find where are the recipes for estrogen detox.

Podano Prema
Podano Prema 5pts

It's really an amazing n heart melting story.

Naveen Pedersen
Naveen Pedersen 5pts

I am begining to think this site is more of a headline catcher than a source of valuable infomation. So how does one detox estrogen?

Tami Bradford Johnson
Tami Bradford Johnson 5pts

What a worthless article as it didn't even tell detox ingredients or recipe. Almost like a joke without a punch line.

Andrea Sadock
Andrea Sadock 5pts

So how do you do it? That was a lot of mumbo jumbo

Susie Sturgeon
Susie Sturgeon 5pts

Did not have a clue we needed to detox estrogen! Intetesting

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Midhuna Vaish 5pts

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